WebMD provides important information about Fioricet Oral such as if you can you take Fioricet Oral when you are pregnant or nursing or If Fioricet Oral dangerous Severe Precaution: Safety and effectiveness not established age. So i'm such an idiot i took fioricet throughout my whole pregnancy for re-read the warnings. turns out it says to not take it while BFing. i am Headaches- Fioricet? — The Bump. I did not take it during pregnancy (though I needed it) but did start taking it again The butalbital is classified as "moderately safe" in Dr. Hale's.